Targeted therapies for cancerMolecularly targeted anticancer agents; MTAs; Chemotherapy-targeted; Vascular endothelial growth factor-targeted; VEGF-targeted; VEGFR-targeted; Tyrosine kinase inhibitor-targeted; TKI-targeted; Personalized medicine - cancer
Targeted therapy uses drugs to stop cancer from growing and spreading. It does this with less harm to normal cells than other treatments.
Standard chemotherapy works by killings cancer cells and some normal cells, targeted treatment zeroes in on specific targets (molecules) in or on cancer cells. These targets play a role in how cancer cells grow and survive. Using these targets, the drug disables the cancer cells so they cannot spread.
Do KT, Kummar S. Therapeutic targeting of cancer cells: era of molecularly targeted agents. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 26.
National Cancer Institute website. Targeted cancer therapies. www.cancer.gov/about-cancer/treatment/types/targeted-therapies/targeted-therapies-fact-sheet. Updated March 17. 2020. Accessed March 20, 2020.