Fecal immunochemical test (FIT)Immunochemical fecal occult blood test; iFOBT; Colon cancer screening - FIT
The fecal immunochemical test (FIT) is a screening test for colon cancer. It tests for hidden blood in the stool, which can be an early sign of cancer. FIT only detects human blood from the lower intestines. Medicines and food do not interfere with the test. So it tends to be more accurate and have fewer false positive results than other tests.
Colorectal cancer is cancer that starts in the large intestine (colon) or the rectum (end of the colon). Other types of cancer can affect the colon. ...Read Article Now Book Mark Article
How the Test is Performed
You will be given the test to use at home. Be sure to follow the instructions provided. Most tests have the following steps:
- Flush the toilet before having a bowel movement.
- Put the used toilet paper in the waste bag provided. Do not put it into the toilet bowl.
- Use the brush from the kit to brush the surface of the stool and then dip the brush into the toilet water.
- Touch the brush on the space indicated on the test card.
- Add the brush to the waste bag and throw it away.
- Send the sample to the lab for testing.
- Your doctor may ask you to test more than one stool sample before sending it in.
How to Prepare for the Test
You do not need to do anything to prepare for the test.
How the Test will Feel
Some people may be squeamish about collecting the sample. But you will not feel anything during the test.
Why the Test is Performed
Blood in the stool may be an early sign of colon cancer. This test is performed to detect blood in the stool that you cannot see. This type of screening can detect problems that can be treated before cancer develops or spreads.
Talk with your doctor about when you should have colon screenings.
Colon cancer screening can detect polyps and early cancers in the large intestine. This type of screening can find problems that can be treated befo...Read Article Now Book Mark Article
A normal result means the test did not detect any blood in the stool. However, because cancers in the colon may not always bleed, you may need to do the test a few times to confirm that there is no blood in your stool.
What Abnormal Test Results Mean
If the FIT results come back positive for blood in the stool, your doctor will want to perform other tests, usually including a colonoscopy. The FIT test does not diagnose cancer. Screening tests such as a sigmoidoscopy or colonoscopy can also help detect cancer. Both the FIT test and other screenings can catch colon cancer early, when it is easier to treat.
Sigmoidoscopy is a procedure used to see inside the sigmoid colon and rectum. The sigmoid colon is the area of the large intestine nearest to the re...Read Article Now Book Mark Article
A colonoscopy is an exam that views the inside of the colon (large intestine) and rectum, using a tool called a colonoscope. The colonoscope has a sm...Read Article Now Book Mark Article
There are no risks from using the FIT.
Itzkowitz SH, Potack J. Colonic polyps and polyposis syndromes. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126.
Lawler M, Johnston B, Van Schaeybroeck S, et al. Colorectal cancer. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 74.
Rex DK, Boland CR, Dominitz JA, et al. Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2017;112(7):1016-1030. PMID: 28555630 www.ncbi.nlm.nih.gov/pubmed/28555630.
Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018;68(4):250-281. PMID: 29846947 www.ncbi.nlm.nih.gov/pubmed/29846947.
Review Date: 7/13/2019
Reviewed By: Michael M. Phillips, MD, Clinical Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.